Title :
Photostimulator for optogenetic retinal prosthesis
Author :
Grossman, N. ; Nikolic, K. ; Poher, V. ; McGovern, B. ; Drankasis, E. ; Neil, Mark ; Toumazou, Christofer ; Degenaar, P.
Author_Institution :
Inst. of Biomed. Eng., Imperial Coll. London, London, UK
fDate :
April 29 2009-May 2 2009
Abstract :
The discovery that neurons can be photostimulated via genetic incorporation of artificial opsins offers potential for many new forms of neural prosthesis. In this work, we demonstrate a photostimulator which has both the irradiance requirement and the spatial resolution for retinal prosthesis. We characterise its electrical and optical properties and show its ability to accurately stimulate individual action potentials.
Keywords :
bio-optics; bioelectric potentials; eye; genetics; neurophysiology; prosthetics; proteins; action potential stimulation; artificial opsin genetic incorporation; neural prosthesis; optogenetic retinal prosthesis; photostimulator; retinal prosthesis electrical property; retinal prosthesis optical property; spatial resolution; Biomedical engineering; Blindness; Neural engineering; Neural prosthesis; Neurons; Neuroscience; Photoreceptors; Physics; Prosthetics; Retina; ChR2; Gallium nitride; LED; channelrhodopsin; neuroprosthesis; optogenetic; retinal prosthesis;
Conference_Titel :
Neural Engineering, 2009. NER '09. 4th International IEEE/EMBS Conference on
Conference_Location :
Antalya
Print_ISBN :
978-1-4244-2072-8
Electronic_ISBN :
978-1-4244-2073-5
DOI :
10.1109/NER.2009.5109236
