Photostimulator for optogenetic retinal prosthesis

Author

Grossman, N. ; Nikolic, K. ; Poher, V. ; McGovern, B. ; Drankasis, E. ; Neil, Mark ; Toumazou, Christofer ; Degenaar, P.

Author_Institution

Inst. of Biomed. Eng., Imperial Coll. London, London, UK

fYear

2009

fDate

April 29 2009-May 2 2009

Firstpage

68

Lastpage

71

Abstract

The discovery that neurons can be photostimulated via genetic incorporation of artificial opsins offers potential for many new forms of neural prosthesis. In this work, we demonstrate a photostimulator which has both the irradiance requirement and the spatial resolution for retinal prosthesis. We characterise its electrical and optical properties and show its ability to accurately stimulate individual action potentials.

Keywords

bio-optics; bioelectric potentials; eye; genetics; neurophysiology; prosthetics; proteins; action potential stimulation; artificial opsin genetic incorporation; neural prosthesis; optogenetic retinal prosthesis; photostimulator; retinal prosthesis electrical property; retinal prosthesis optical property; spatial resolution; Biomedical engineering; Blindness; Neural engineering; Neural prosthesis; Neurons; Neuroscience; Photoreceptors; Physics; Prosthetics; Retina; ChR2; Gallium nitride; LED; channelrhodopsin; neuroprosthesis; optogenetic; retinal prosthesis;

fLanguage

English

Publisher

ieee

Conference_Titel

Neural Engineering, 2009. NER '09. 4th International IEEE/EMBS Conference on

Conference_Location

Antalya

Print_ISBN

978-1-4244-2072-8

Electronic_ISBN

978-1-4244-2073-5

Type

conf

DOI

10.1109/NER.2009.5109236

Filename

5109236