Title :
Application of photonic crystal enhanced fluorescence to antibody microarrays
Author :
Huang, Cheng-Sheng ; George, Sherine ; Lu, Meng ; Chaudhery, Vikram ; Tan, Ruimin ; Zangar, Richard C. ; Cunningham, Brian T.
Author_Institution :
Dept. of Electr. & Comput. Eng., Univ. of Illinois, Urbana, IL, USA
Abstract :
A photonic crystal surface is utilized for detection of cancer biomarkers in a fluorescent-tagged protein microarray assay. The results indicates that the detection limit of assays are reduced by up to 90% through resonant illumination.
Keywords :
bio-optics; biosensors; cancer; fluorescence; photonic crystals; proteins; antibody microarray; cancer biomarker detection; fluorescent-tagged protein microarray assay; photonic crystal enhanced fluorescence; photonic crystal surface; resonant illumination; Biomarkers; Cancer; Fluorescence; Gratings; Photonic crystals; Proteins; Scanning electron microscopy;
Conference_Titel :
Lasers and Electro-Optics (CLEO), 2011 Conference on
Conference_Location :
Baltimore, MD
Print_ISBN :
978-1-4577-1223-4
