DocumentCode :
2228306
Title :
An equivalent Markov model for Gillespie´s Stochastic Simulation Algorithm for biochemical systems
Author :
Bustin, Ronit ; Messer, Hagit
Author_Institution :
Sch. of Electr. Eng., Tel-Aviv Univ., Tel-Aviv, Israel
fYear :
2006
fDate :
4-8 Sept. 2006
Firstpage :
1
Lastpage :
5
Abstract :
Mathematical/statistical modeling of biological systems is a desired goal for many years. It aims to be able to accurately predict the operation of such systems under various scenarios using computer simulations. In this paper we revisit Gillespie´s Stochastic Simulation Algorithm for biochemical systems and we suggest an equivalent Markov Model for it. We show that under certain conditions it is a 1st order homogenous Markov process and we analyze these conditions. Our suggested model can be used to simulate the probability density function of a biochemical processes which, in turn, can be used for applying statistical signal processing and information theory tools on them.
Keywords :
DNA; Markov processes; information theory; probability; signal processing; 1st order homogenous Markov process; Gillespie stochastic simulation; biochemical process; biochemical systems; biological systems; computer simulations; equivalent Markov model; information theory; mathematical modeling; probability density function; statistical modeling; statistical signal processing; Abstracts; Biological system modeling; Mathematical model; Radiation detectors; Tin; Vectors;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Signal Processing Conference, 2006 14th European
Conference_Location :
Florence
ISSN :
2219-5491
Type :
conf
Filename :
7071767
Link To Document :
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