Title :
Analysis of amino acid parameters in the Resonant Recognition Model
Author :
Pirogova, Elena ; Fang, Qiang ; Lazoura, Eliada ; Cosic, Irena
Author_Institution :
Monash Univ., Vic., Australia
Abstract :
The Resonant Recognition Model (RRM) is a physicomathematical model developed for analysing protein and nucleic acid sequences. Previously, the electron-ion interaction potentials (EIIP) of amino acids have been used to determine the characteristic frequency of biologically related proteins. In this study, the effect of various other amino acid parameters on periodicity, obtained using the RRM, were assessed. Three functionally unrelated protein groups (glucagons, lysozymes and haemoglobins) were used as test examples. However, no single parameter was found to be a good representative of biological activity
Keywords :
Fourier analysis; biochemistry; correlation methods; macromolecules; molecular biophysics; molecular configurations; proteins; spectral analysis; Fourier transform; amino acid parameters analysis; average energy states; biological activity; characteristic frequency; correlation coefficients; cross-spectral analysis; electron-ion interaction potentials; glucagons; haemoglobins; lysozymes; nucleic acid sequences; numerical series; periodicity; physicomathematical model; protein sequences; resonant recognition model; valence electrons; Amino acids; Databases; Frequency; Hip; Hydrogen; Indexes; Protein engineering; Resonance; Signal analysis; Systems engineering and theory;
Conference_Titel :
Bioelectromagnetism, 1998. Proceedings of the 2nd International Conference on
Conference_Location :
Melbourne, Vic.
Print_ISBN :
0-7803-3867-7
DOI :
10.1109/ICBEM.1998.666400
