Title :
Magnetite core-inorganic shell nanoparticles for biomedical applications by novel confined-zone synthesis
Author :
Salazar-Alvarez, German ; Zagorodni, Andrei A. ; Muhammed, Mamoun
Author_Institution :
Mater. Chem. Div., R. Inst. of Technol., Stockholm, Sweden
Abstract :
The reproducible preparation of homogeneous iron oxide nanoparticles with particle size diameters less than 5 nm and r.s.d. as low as 17% by a novel flow-injection synthesis is described. The particles were directly coated with a layer of amorphous silica with precisely controlled thickness between 4 nm and 20 nm. Thermo-chemical analysis of the particles showed that the silica layer acts as retardant of oxidation thus reducing the availability of Fe(II).
Keywords :
biomagnetism; biomedical materials; chemical analysis; iron compounds; magnetic particles; materials preparation; nanoparticles; nanotechnology; oxidation; particle size; silicon compounds; thermochemistry; 4 to 20 nm; SiO2-Fe3O4; amorphous silica; biomedical applications; confined-zone synthesis; flow-injection synthesis; homogeneous iron oxide nanoparticles; magnetite core-inorganic shell nanoparticles; oxidation; particle size; preparation; thermo-chemical analysis; thickness; Amorphous magnetic materials; Amorphous materials; Iron; Magnetic confinement; Magnetic cores; Nanoparticles; Oxidation; Retardants; Silicon compounds; Thickness control;
Conference_Titel :
Nanotechnology, 2002. IEEE-NANO 2002. Proceedings of the 2002 2nd IEEE Conference on
Print_ISBN :
0-7803-7538-6
DOI :
10.1109/NANO.2002.1032128