DocumentCode :
2248307
Title :
Metabolic networks analysis using convex optimization
Author :
Julius, A. Agung ; Imielinski, Marcin ; Pappas, George J.
Author_Institution :
Dept. Electr. & Syst. Eng., Univ. of Pennsylvania, Philadelphia, PA, USA
fYear :
2008
fDate :
9-11 Dec. 2008
Firstpage :
762
Lastpage :
767
Abstract :
Metabolic networks map the biochemical reactions in a living cell to the flow of various chemical substances in the cell, which are called metabolites. A standard model of a metabolic network is given as a linear map from the reaction rates to the change in metabolites concentrations. We study two problems related to the analysis of metabolic networks, the minimal network problem and the minimal knockout problem.
Keywords :
optimisation; biochemical reactions; chemical substances; convex optimization; metabolic networks analysis; metabolites concentrations; minimal knockout problem; minimal network problem; Biochemistry; Bioinformatics; Biological system modeling; Cells (biology); Cellular networks; Genomics; Organisms; Production; Steady-state; Systems biology;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Decision and Control, 2008. CDC 2008. 47th IEEE Conference on
Conference_Location :
Cancun
ISSN :
0191-2216
Print_ISBN :
978-1-4244-3123-6
Electronic_ISBN :
0191-2216
Type :
conf
DOI :
10.1109/CDC.2008.4739111
Filename :
4739111
Link To Document :
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