Title :
Prediction of subcelluar localization using maximal-margin spherical support vector machine
Author :
Chen, Wei-ming ; Wu, I-lin ; Chiang, Jung-Hsien ; Hao, Pei-Yi
Author_Institution :
Dept. of Comput. Sci. & Inf. Eng., Nat. Cheng Kung Univ., Tainan, Taiwan
Abstract :
Prediction of subcellular localization of various proteins is an important and well-studied problem. Each compartment in cell has specific tasks, and proteins in each compartment are synthesized to fulfill these tasks, and for this reason, an effective predictive system for protein subcellular localization is crucial. Therefore, we propose a prediction based on maximal margin sphere-structure multi-class support vector, and use some different types of composition in amino acid for features. The experimental results show that the proposed method is better than transitional support vector machine.
Keywords :
bioinformatics; cellular biophysics; pattern classification; proteins; support vector machines; amino acid; bioinformatics; maximal margin sphere-structure multiclass support vector; maximal-margin spherical support vector machine; predictive system; protein; spherical classifier; subcelluar localization; Accuracy; Amino acids; Bioinformatics; Kernel; Machine learning; Proteins; Support vector machines; Bioinformatics; Prediction of Subcellular Localization; Spherical Classifier; Support Vector Machine; Tracking;
Conference_Titel :
Machine Learning and Cybernetics (ICMLC), 2010 International Conference on
Conference_Location :
Qingdao
Print_ISBN :
978-1-4244-6526-2
DOI :
10.1109/ICMLC.2010.5580840