Title :
Molecular interferometric imaging biosensor to study molecular interactions
Author :
Zhao, Ming ; Wang, Xuefeng ; Nolte, David
Author_Institution :
Dept. of Phys., Purdue Univ., West Lafayette, IN
Abstract :
Molecular interferometric imaging (MI2) approaches the single-molecule limit for label-free direct optical detection. It is simpler, cheaper and more sensitive than surface plasmon resonance for dynamic studies of molecular interactions.
Keywords :
bio-optics; biochemistry; biological techniques; biosensors; light interferometry; molecular biophysics; optical images; optical sensors; proteins; label-free direct optical detection; molecular dynamic studies; molecular interactions; molecular interferometric imaging biosensor; proteins; Biomedical optical imaging; Biosensors; Optical imaging; Optical interferometry; Optical refraction; Optical scattering; Optical sensors; Optical surface waves; Optical variables control; Proteins; (170.1470) Blood/tissue constituent monitoring; (180.3170) Interference microscopy;
Conference_Titel :
Lasers and Electro-Optics, 2008 and 2008 Conference on Quantum Electronics and Laser Science. CLEO/QELS 2008. Conference on
Conference_Location :
San Jose, CA
Print_ISBN :
978-1-55752-859-9