Silicon micromachined hollow microneedles for transdermal liquid transfer

Author

Gardeniers, J.G.E. ; Berenschot, J.W. ; de Boer, M.J. ; Yeshurun, Y. ; Hefetz, M. ; van´t Oever, R. ; van den Berg, A.

Author_Institution

Micronit Microfluidics B.V, Enschede, Netherlands

fYear

2002

fDate

24-24 Jan. 2002

Firstpage

141

Lastpage

144

Abstract

This paper presents an improved design and fabrication process for hollow micro needles with the proper mechanical strength and sharpness to be applied for painless transdermal transfer of liquids. Tests have shown that liquids like blood are drawn into the needle by capillary forces, reducing the need for active pumping. The fabrication method allows different needle shapes like blades and pencils, is robust enough to be applied for larger scale production, and enables the development of a complete micro-TAS for e.g. blood analysis.

Keywords

blood; drug delivery systems; elemental semiconductors; micromachining; silicon; MEMS technology; Si; blood extraction; capillary force; drug delivery; fabrication process; hollow microneedle; medical microsystem; micro-total analysis system; silicon micromachining; transdermal liquid transfer; Blades; Blood; Fabrication; Liquids; Needles; Process design; Robustness; Shape; Silicon; Testing;

fLanguage

English

Publisher

ieee

Conference_Titel

Micro Electro Mechanical Systems, 2002. The Fifteenth IEEE International Conference on

Conference_Location

Las Vegas, NV, USA

ISSN

1084-6999

Print_ISBN

0-7803-7185-2

Type

conf

DOI

10.1109/MEMSYS.2002.984224

Filename

984224