Title :
Recognition of double-stranded DNA by gold nanoprobes for malignant melanoma detection
Author :
Ahn, Jihye ; Park, Wounjhang ; Bemis, Lynne ; Robinson, William A.
Author_Institution :
Dept. of Electr. & Comput. Eng., Univ. of Colorado, Boulder, CO
Abstract :
We report the detection of mutated BRAF gene expressed in malignant melanoma. We demonstrate the detection of short and long, single- and double-stranded DNAs using gold nanoprobes.
Keywords :
DNA; bio-optics; cancer; genetics; gold; molecular biophysics; nanobiotechnology; skin; surface plasmons; tumours; aggregates formation; double-stranded DNA recognition; field emission scanning electron-microscope; gold nanoprobes; malignant melanoma; malignant melanoma detection; mutated BRAF gene expression; surface plasmon peak shift; Aggregates; Cancer; DNA; Gold; Malignant tumors; Nanoparticles; Plasmons; Probes; Spectroscopy; Ultrafast optics; (170.4580) Optical diagnostics for medicine; (170.6510) Spectroscopy, tissue diagnostics;
Conference_Titel :
Lasers and Electro-Optics, 2008 and 2008 Conference on Quantum Electronics and Laser Science. CLEO/QELS 2008. Conference on
Conference_Location :
San Jose, CA
Print_ISBN :
978-1-55752-859-9
