Title :
Closed-loop eyelid reanimation system with real-time blink detection and electrochemical stimulation for facial nerve paralysis
Author :
Chen, Kuanfu ; Chen, Tung-Chien ; Cockerham, Kimberly ; Liu, Wentai
Author_Institution :
Univ. of California, Santa Cruz, CA, USA
Abstract :
Electrical stimulation in eyelid reanimation has been verified in previous studies as a potential treatment for facial nerve paralysis. Design challenges, including physical pain during stimulation, reducing the latency between the natural blink and the artificial blink, and patient-to-patient differences, make it difficult to build this system. In this paper, the design challenges are analyzed in detail, based on which a closed-loop electrochemical stimulation system is proposed. Using our system, real-time blink detection and electrical stimulation have been verified with FPGA and ASICs. Area of the proposed fully integrated chip, including electromyography (EMG) amplifier, blink detection processor, reduced instruction set computer (RISC), and current stimulator, is estimated to be 11.46 mm2 in 0.35 um CMOS process.
Keywords :
CMOS integrated circuits; application specific integrated circuits; computer animation; electrochemical analysis; electromyography; field programmable gate arrays; medical computing; object detection; patient treatment; reduced instruction set computing; 0.35 um CMOS process; ASICs; FPGA; blink detection processor; closed-loop eyelid reanimation system; electrochemical stimulation; electromyography amplifier; facial nerve paralysis treatment; real-time blink detection; reduced instruction set computer; Computer aided instruction; Delay; Electrical stimulation; Electromyography; Eyelids; Face detection; Field programmable gate arrays; Pain; Real time systems; Reduced instruction set computing;
Conference_Titel :
Circuits and Systems, 2009. ISCAS 2009. IEEE International Symposium on
Conference_Location :
Taipei
Print_ISBN :
978-1-4244-3827-3
Electronic_ISBN :
978-1-4244-3828-0
DOI :
10.1109/ISCAS.2009.5117807
