• DocumentCode
    2254259
  • Title

    Coupling effects in networks of cyclic negative feedback systems

  • Author

    Lanza, Valentina ; Corinto, Fernando ; Gilli, Marco

  • Author_Institution
    Dept. of Phys., Politec. di Torino, Torino, Italy
  • fYear
    2009
  • fDate
    24-27 May 2009
  • Firstpage
    852
  • Lastpage
    855
  • Abstract
    Negative feedback control loops are widely used in numerous models of periodic phenomena occurring in systems biology, since they give rise to sustained oscillations. In particular, the possible coexistence of different attractors permits to suitably describe the differentiating processes arising in the cell. The aim of this work is to study coupled systems of such kind through spectral techniques, in order to characterize the various complex dynamical behaviors that can emerge due to the couplings.
  • Keywords
    biology; feedback; large-scale systems; time-varying systems; complex dynamical behavior; coupling effects; cyclic negative feedback systems; negative feedback control loop; periodic phenomena; spectral techniques; systems biology; Biological system modeling; Circadian rhythm; Clocks; Feedback control; Limit-cycles; Nearest neighbor searches; Negative feedback; Negative feedback loops; Physics; Systems biology;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Circuits and Systems, 2009. ISCAS 2009. IEEE International Symposium on
  • Conference_Location
    Taipei
  • Print_ISBN
    978-1-4244-3827-3
  • Electronic_ISBN
    978-1-4244-3828-0
  • Type

    conf

  • DOI
    10.1109/ISCAS.2009.5117890
  • Filename
    5117890
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=2254259