• DocumentCode
    2254789
  • Title

    Recognition of staphylococcus aureus by new carborane derivative

  • Author

    Lv, Xiayi ; Li, Shuihong ; Liu, Wei ; Yan, Hong ; Wang, Xuemei

  • Author_Institution
    State Key Lab. of Bioelectronics, Southeast Univ., Nanjing, China
  • fYear
    2012
  • fDate
    5-7 Jan. 2012
  • Firstpage
    163
  • Lastpage
    165
  • Abstract
    The effects of different molecules on inducing the multi-drug resistant bacteria to apoptosis and reversing their multi-drug resistance are a prevalent topic in the sciences. In this report we have explored the possibility to utilize a new carborane-ferrocene derivative in recognizing and inhibiting the growth of clinical multidrug-resistant (MDR) pathogenic bacteria. The results illustrate the specific interaction between the new carborane-ferrocene derivative and bacteria, which can readily induce bacteria cell apoptosis and inhibit the growth of the drug-resistant bacteria like staphylococcus aureus.
  • Keywords
    biochemistry; drugs; microorganisms; molecular biophysics; MDR pathogenic bacteria; Staphylococcus aureus recognition; apoptosis; carborane derivative; carborane-ferrocene derivative; clinical multidrug-resistant growth; molecules; multidrug resistant bacteria; Anti-bacterial; Biology; Biosensors; Chemicals; Educational institutions; Microwave integrated circuits;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Biomedical and Health Informatics (BHI), 2012 IEEE-EMBS International Conference on
  • Conference_Location
    Hong Kong
  • Print_ISBN
    978-1-4577-2176-2
  • Electronic_ISBN
    978-1-4577-2175-5
  • Type

    conf

  • DOI
    10.1109/BHI.2012.6211534
  • Filename
    6211534