Title :
Recognition of staphylococcus aureus by new carborane derivative
Author :
Lv, Xiayi ; Li, Shuihong ; Liu, Wei ; Yan, Hong ; Wang, Xuemei
Author_Institution :
State Key Lab. of Bioelectronics, Southeast Univ., Nanjing, China
Abstract :
The effects of different molecules on inducing the multi-drug resistant bacteria to apoptosis and reversing their multi-drug resistance are a prevalent topic in the sciences. In this report we have explored the possibility to utilize a new carborane-ferrocene derivative in recognizing and inhibiting the growth of clinical multidrug-resistant (MDR) pathogenic bacteria. The results illustrate the specific interaction between the new carborane-ferrocene derivative and bacteria, which can readily induce bacteria cell apoptosis and inhibit the growth of the drug-resistant bacteria like staphylococcus aureus.
Keywords :
biochemistry; drugs; microorganisms; molecular biophysics; MDR pathogenic bacteria; Staphylococcus aureus recognition; apoptosis; carborane derivative; carborane-ferrocene derivative; clinical multidrug-resistant growth; molecules; multidrug resistant bacteria; Anti-bacterial; Biology; Biosensors; Chemicals; Educational institutions; Microwave integrated circuits;
Conference_Titel :
Biomedical and Health Informatics (BHI), 2012 IEEE-EMBS International Conference on
Conference_Location :
Hong Kong
Print_ISBN :
978-1-4577-2176-2
Electronic_ISBN :
978-1-4577-2175-5
DOI :
10.1109/BHI.2012.6211534
