Title :
A neuronal network model with STDP for tinnitus and its management by sound therapy
Author :
Nagashino, Hirofumi ; Kinouchi, Yohsuke ; Danesh, Ali A. ; Pandya, Abhijit S.
Author_Institution :
Dept. of Biomed. Inf. Sci., Univ. of Tokushima, Tokushima, Japan
Abstract :
Tinnitus is a phantom sound that one hears in the ears or in the head without any external source. Sound therapy is one of the most effective techniques for tinnitus treatment that have been proposed. In order to investigate mechanisms of tinnitus generation and the clinical effects of sound therapy, we have proposed computational models with plasticity using a neural oscillator or a neuronal network model described by simplified Hodgkin-Huxley equations. In the present paper, another neuronal network model with a different structure based on a recent physiological consideration is proposed and the simulation results of the model are described. The model is able to replicate the clinical results that human auditory system temporarily halts perception of tinnitus following sound therapy.
Keywords :
ear; hearing; neural nets; neurophysiology; patient treatment; phantoms; plasticity; STDP; ears; human auditory system; neural oscillator; neuronal network model; phantom sound; physiological consideration; plasticity; simplified Hodgkin-Huxley equations; sound therapy; tinnitus treatment; Biological system modeling; Computational modeling; Electronic mail; Humans; Medical treatment; Nervous system; Unified modeling language;
Conference_Titel :
Biomedical and Health Informatics (BHI), 2012 IEEE-EMBS International Conference on
Conference_Location :
Hong Kong
Print_ISBN :
978-1-4577-2176-2
Electronic_ISBN :
978-1-4577-2175-5
DOI :
10.1109/BHI.2012.6211607