Title :
Near-infrared fluorescent labeling of tissue transglutaminase substrates for imaging tumor boundaries
Author :
Pan, Chia Pin ; Amin, Khalid ; Shi, Yihui ; Olson, Stephanie ; Haushalter, Jeanne P. ; Greenberg, Charles S. ; Haroon, Zishan ; Faris, Gregory W.
Author_Institution :
Phys. Sci. Div., SRI Int., Menlo Park, CA
Abstract :
A novel strategy is developed to optically image tumor boundaries by cross-linking near-infrared fluorescent-labeled tissue trans glutaminase substrates into tumor boundary tissue.
Keywords :
biomedical optical imaging; cancer; enzymes; fluorescence; infrared imaging; molecular biophysics; tumours; near-infrared fluorescent labeling; tissue transglutaminase substrate; tumor boundary imaging; Biomedical imaging; Biomedical optical imaging; Cancer; Electrochemical machining; Fluorescence; Labeling; Medical diagnostic imaging; Neoplasms; Optical imaging; Wounds; (170.0110) Imaging systems; (170.4580) Optical diagnostics for medicine; (170.6280) Spectroscopy, fluorescence and luminescence;
Conference_Titel :
Lasers and Electro-Optics, 2008 and 2008 Conference on Quantum Electronics and Laser Science. CLEO/QELS 2008. Conference on
Conference_Location :
San Jose, CA
Print_ISBN :
978-1-55752-859-9
