Study of pressure estimation for a human circulatory system with a LVAD

Author

Wu, Yi ; Allaire, Paul ; Tao, Gang ; Olsen, Don

Author_Institution

Dept. of Mech. Eng., Pennsylvania State Univ., Erie, PA

fYear

2006

fDate

14-16 June 2006

Abstract

Physiological control of a left ventricular assist device (LVAD) is related to the control of blood pressure. Based on the state space model of human circulatory system, the mean aortic pressure can be estimated. This paper is to study the estimation error in the presence of variations of heart rate, systole vs. diastole ratio, left ventricular contractility, resistance of blood vessels, aortic compliance. These variations may occur during the working life of a long term LVAD. Our paper demonstrated that the estimator can track the large variation of resistance, and the performance depends on the accuracy of the value for an artificial parameter and the peak to peak (p-p) value of LVAD flow rate. Simulation results showed that the value of this artificial parameter is varying in different scenarios. The result of this paper can be utilized for control of long term LVADs, or for non-invasive evaluation of left ventricular function and human circulatory system properties

Keywords

blood vessels; medical control systems; prosthetics; state-space methods; cardiovascular system; human circulatory system; left ventricular assist device; mean aortic pressure estimation; physiological control; state space model; Blood pressure; Blood vessels; Circulatory system; Estimation error; Heart rate; Humans; Immune system; Pressure control; State estimation; State-space methods;

fLanguage

English

Publisher

ieee

Conference_Titel

American Control Conference, 2006

Conference_Location

Minneapolis, MN

Print_ISBN

1-4244-0209-3

Electronic_ISBN

1-4244-0209-3

Type

conf

DOI

10.1109/ACC.2006.1655440

Filename

1655440