Title :
Magneto-optical phase enantiomeric detector
Author :
Gibbs, P. ; Kimmel, Melanie ; Bommarius, A. ; Trebino, Rick
Author_Institution :
Georgia Inst. of Technol., Atlanta, GA, USA
Abstract :
Summary from only given. We have developed improved techniques for rapidly and sensitively screening potential medicines. These include the Faraday effect using a sinusoidally varying magnetic field, phase-sensitive detection, and optical-heterodyne detection. We call this set of techniques and the resulting device the magneto-optical phase enantiomeric detector (MOPED). Because chiral molecules on average exhibit greater Faraday effect than non-chiral molecules and our two detection methods are extremely sensitive and fast, these techniques provide increased sensitivity and decreased analysis time.
Keywords :
Faraday effect; biological techniques; chirality; magneto-optical sensors; medicine; molecular biophysics; optical rotation; Faraday effect; analysis time; chiral molecules; detection methods; magneto-optical phase enantiomeric detector; optical-heterodyne detection; phase-sensitive detection; potential medicines; screening; sensitivity; sinusoidally varying magnetic field; Biomedical optical imaging; Faraday effect; Magnetic analysis; Magnetooptic devices; Magnetooptic effects; Motorcycles; Optical detectors; Optical sensors; Phase detection; Ultraviolet sources;
Conference_Titel :
Lasers and Electro-Optics, 2002. CLEO '02. Technical Digest. Summaries of Papers Presented at the
Conference_Location :
Long Beach, CA, USA
Print_ISBN :
1-55752-706-7
DOI :
10.1109/CLEO.2002.1034139