Title :
Visual fly-throughs of rat osteogenic sarcoma by optical coherence imaging
Author :
Yu, P. ; Mustata, M. ; Nolte, D.D. ; Turek, J.J. ; French, P.M.W.
Author_Institution :
Dept. of Phys., Purdue Univ., West Lafayette, IN, USA
Abstract :
Summary from only given. Present the first visual fly-throughs of living tumor (rat osteogenic sarcoma tumor spheroids) using direct optical imaging. Tumor spheroids were grown to diameters of nearly half a millimeter using a clonal derivative of a transplantable rat osteosarcoma (UMR-106; American Type Culture Collection # CRL-1661, Rockville, MD). By selecting the input intensity on the tumor, the imaging system, and the relative intensity between the signal and reference beams, we successfully obtained the fly-throughs of rat tumor spheroids (a characteristic data-volume is shown. Larger spheroids have increasingly complex inner structure including necrosis, calcification, and fluid-filled voids. These features produce highly structured coherent images.
Keywords :
biomedical optical imaging; optical tomography; tumours; calcification; clonal derivative; fluid-filled voids; highly structured coherent images; imaging system; increasingly complex inner structure; input intensity; necrosis; optical coherence imaging; rat osteogenic sarcoma; reference beam; relative intensity; signal beam; transplantable rat osteosarcoma; visual fly-throughs; Biomedical imaging; Biomedical optical imaging; Holographic optical components; Holography; Optical filters; Optical imaging; Optical interferometry; Optical scattering; Optical sensors; Ultrafast optics;
Conference_Titel :
Lasers and Electro-Optics, 2002. CLEO '02. Technical Digest. Summaries of Papers Presented at the
Conference_Location :
Long Beach, CA, USA
Print_ISBN :
1-55752-706-7
DOI :
10.1109/CLEO.2002.1034218
