Title :
Design of a novel device for rapid antigen detection
Author :
DeFroda, S. ; Folchman-Wagner, Z. ; Mcguire, J. ; Movilla, P. ; van de Rijn, M.
Author_Institution :
Stevens Inst. of Technol., Hoboken, NJ, USA
Abstract :
A compact, hand-held device was designed to determine the presence of the C. trachomatis antigen in a sample in under 2 minutes. The point-of-care device uses magnetic assay cell separation techniques involving the molecular interactions between polystyrene beads, C. trachomatis antigen and magnetic beads. In the result of a positive test, a complex forms and induces a color change. In the result of a negative test, no complex forms, and thus, no color change occurs.
Keywords :
biomagnetism; biomedical equipment; chemical sensors; molecular biophysics; proteins; C. trachomatis antigen; Chlamydia trachomatis; color change; hand-held device; magnetic assay cell separation techniques; magnetic beads; molecular interactions; point-of-care device; polystyrene beads; rapid antigen detection; Bacterial infections; Biomembranes; Fasteners; Magnetic devices; Magnetic fields; Magnetic separation; Medical diagnostic imaging; Medical tests; Performance evaluation; Testing;
Conference_Titel :
Bioengineering Conference, Proceedings of the 2010 IEEE 36th Annual Northeast
Conference_Location :
New York, NY
Print_ISBN :
978-1-4244-6879-9
DOI :
10.1109/NEBC.2010.5458228
