• DocumentCode
    2274591
  • Title

    In vivo fluorescence of 101.8 rat brain tumours sensitized by 5-ALA-induced porphyrins

  • Author

    Ciburys, A. ; Gadonas, D. ; Gadonas, Roaldas ; Kaskelyte, D. ; Piskarskas, A. ; Smilgevicius, Valerijus ; Didziapetriene, J. ; Grazeliene, G. ; Sukackaite, A. ; Gudinaviciene, I. ; Skauminas, K.

  • Author_Institution
    Laser Res. Centre, Vilnius Univ., Lithuania
  • fYear
    2002
  • fDate
    24-24 May 2002
  • Firstpage
    560
  • Abstract
    Summary from only given. We present, for the first time to our knowledge, observation of in vivo fluorescence of 5-ALA-induced PpIX in 101.8 brain tumours. All the experiments reported have been performed in the conditions close to intraoperative.We conclude that in vivo registration of 5-ALA induced PpIX fluorescence at the time after ALA injection corresponding to maximum tumour-to-host contrast offers a possibility to detect and visualize cerebral glioma 101.8 intraoperatively.
  • Keywords
    biochemistry; brain; fluorescence; surgery; tumours; 5-ALA-induced PpIX; 5-ALA-induced porphyrins; in vivo fluorescence; intraoperative conditions; maximum tumour-to-host contrast; rat brain tumours; Biomedical imaging; Biomedical optical imaging; Fluorescence; In vivo; Laser excitation; Laser theory; Optical imaging; Physics; Spectroscopy; Tumors;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Lasers and Electro-Optics, 2002. CLEO '02. Technical Digest. Summaries of Papers Presented at the
  • Conference_Location
    Long Beach, CA, USA
  • Print_ISBN
    1-55752-706-7
  • Type

    conf

  • DOI
    10.1109/CLEO.2002.1034324
  • Filename
    1034324