Title :
In vivo fluorescence of 101.8 rat brain tumours sensitized by 5-ALA-induced porphyrins
Author :
Ciburys, A. ; Gadonas, D. ; Gadonas, Roaldas ; Kaskelyte, D. ; Piskarskas, A. ; Smilgevicius, Valerijus ; Didziapetriene, J. ; Grazeliene, G. ; Sukackaite, A. ; Gudinaviciene, I. ; Skauminas, K.
Author_Institution :
Laser Res. Centre, Vilnius Univ., Lithuania
Abstract :
Summary from only given. We present, for the first time to our knowledge, observation of in vivo fluorescence of 5-ALA-induced PpIX in 101.8 brain tumours. All the experiments reported have been performed in the conditions close to intraoperative.We conclude that in vivo registration of 5-ALA induced PpIX fluorescence at the time after ALA injection corresponding to maximum tumour-to-host contrast offers a possibility to detect and visualize cerebral glioma 101.8 intraoperatively.
Keywords :
biochemistry; brain; fluorescence; surgery; tumours; 5-ALA-induced PpIX; 5-ALA-induced porphyrins; in vivo fluorescence; intraoperative conditions; maximum tumour-to-host contrast; rat brain tumours; Biomedical imaging; Biomedical optical imaging; Fluorescence; In vivo; Laser excitation; Laser theory; Optical imaging; Physics; Spectroscopy; Tumors;
Conference_Titel :
Lasers and Electro-Optics, 2002. CLEO '02. Technical Digest. Summaries of Papers Presented at the
Conference_Location :
Long Beach, CA, USA
Print_ISBN :
1-55752-706-7
DOI :
10.1109/CLEO.2002.1034324
