Study on Si-surface modification with chitosan and cell adhesion

Author

Wei, Cui ; Xiaoying, Lü ; Zhigong, Wang ; Yi, Zhao

Author_Institution

State Key Lab. of Bioelectron., Southeast Univ., Nanjing

fYear

2008

fDate

1-3 June 2008

Firstpage

53

Lastpage

54

Abstract

Chitoan was immobilized on silicon surface by(3-aminopropyl) triethoxysilane (APTES) ldquobridgerdquo. Contact angle measurement and Auger electron spectroscopy (AES) was used to characterize steps of the process. L929 Cells were used to evaluate the biology effect of the modification. The results have shown that the chitosan modification could depress the adhesion of cells on silicon.

Keywords

Auger electron spectra; adhesion; biomedical materials; biomimetics; biotechnology; cellular biophysics; contact angle; silicon; surface treatment; (3-aminopropyl) triethoxysilane; APTES bridge; Auger electron spectroscopy; L929 cells; Si; cell adhesion; chitosan modification; contact angle measurement; silicon surface modification; Adhesives; Biological materials; Biosensors; Cells (biology); Chemical analysis; Goniometers; Silicon; Substrates; Surface cleaning; Surface treatment; cell adhesion; chitosan; modification; silicon;

fLanguage

English

Publisher

ieee

Conference_Titel

Medical Devices and Biosensors, 2008. ISSS-MDBS 2008. 5th International Summer School and Symposium on

Conference_Location

Hong Kong

Print_ISBN

978-1-4244-2252-4

Electronic_ISBN

978-1-4244-2253-1

Type

conf

DOI

10.1109/ISSMDBS.2008.4575014

Filename

4575014