Title :
Study on Si-surface modification with chitosan and cell adhesion
Author :
Wei, Cui ; Xiaoying, Lü ; Zhigong, Wang ; Yi, Zhao
Author_Institution :
State Key Lab. of Bioelectron., Southeast Univ., Nanjing
Abstract :
Chitoan was immobilized on silicon surface by(3-aminopropyl) triethoxysilane (APTES) ldquobridgerdquo. Contact angle measurement and Auger electron spectroscopy (AES) was used to characterize steps of the process. L929 Cells were used to evaluate the biology effect of the modification. The results have shown that the chitosan modification could depress the adhesion of cells on silicon.
Keywords :
Auger electron spectra; adhesion; biomedical materials; biomimetics; biotechnology; cellular biophysics; contact angle; silicon; surface treatment; (3-aminopropyl) triethoxysilane; APTES bridge; Auger electron spectroscopy; L929 cells; Si; cell adhesion; chitosan modification; contact angle measurement; silicon surface modification; Adhesives; Biological materials; Biosensors; Cells (biology); Chemical analysis; Goniometers; Silicon; Substrates; Surface cleaning; Surface treatment; cell adhesion; chitosan; modification; silicon;
Conference_Titel :
Medical Devices and Biosensors, 2008. ISSS-MDBS 2008. 5th International Summer School and Symposium on
Conference_Location :
Hong Kong
Print_ISBN :
978-1-4244-2252-4
Electronic_ISBN :
978-1-4244-2253-1
DOI :
10.1109/ISSMDBS.2008.4575014