Title :
Spin coated thin-film polymer waveguide Mach-Zehnder interferometer for label-free streptavidin detection
Author :
Bruck, R. ; Melnik, E. ; Muellner, P. ; Hainberger, R. ; Lämmerhofer, M.
Author_Institution :
Health & Environ., AIT Austrian Inst. of Technol. GmbH, Vienna, Austria
Abstract :
We report the development of Mach-Zehnder interferometer biosensors based on spin coated thin-film high index contrast polymer waveguides. Despite the large wavelength of 1310 nm and the comparatively low index contrast in polymers, label-free online detection of streptavidin concentrations as low as 0.1 μg/ml (= 1.66 nMol) was achieved. The polymer-based optical sensor design is fully compatible with cost-efficient mass production technologies such as injection molding and spin coating.
Keywords :
Mach-Zehnder interferometers; biochemistry; biosensors; chemical variables measurement; integrated optics; optical design techniques; optical films; optical sensors; optical waveguides; polymer films; proteins; spin coating; cost-efficient mass production technologies; injection molding; interferometer biosensors; label-free streptavidin concentration detection; polymer-based optical sensor design; spin coated thin-film polymer waveguide Mach-Zehnder interferometer; wavelength 1310 nm; Biosensors; Optical interferometry; Optical ring resonators; Optical sensors; Optical waveguides; Polymers;
Conference_Titel :
Information Photonics (IP), 2011 ICO International Conference on
Conference_Location :
Ottawa, ON
Print_ISBN :
978-1-61284-315-5
DOI :
10.1109/ICO-IP.2011.5953810
