DocumentCode :
2302275
Title :
An Optimized Algorithm for Finding Approximate Tandem Repeats in DNA Sequences
Author :
Li, Sheng ; Jiang, Qingshan ; Wei, Dan
Author_Institution :
Software Sch., Xiamen Univ., Xiamen, China
Volume :
3
fYear :
2010
fDate :
6-7 March 2010
Firstpage :
68
Lastpage :
71
Abstract :
In gene analysis, finding approximate tandem repeats in DNA sequence is an important issue. MSATR is one of the latest methods for finding those repetitions, which suffers deficiencies of runtime cost and poor result quality. This paper proposes an optimized algorithm mMSATR for detecting approximate tandem repeats in genomic sequences more efficiently. By introducing the definition of CASM to reduce the searching scope and optimizing the original mechanism adopted by MSATR, mMSATR makes the detecting process more efficient and improves the result quality. The theoretical analysis and experiment results indicates that mMSATR is able to get more results within less runtime. Algorithm mMSATR is superior to other methods in finding results, and it greatly reduces the runtime cost, which is of benefit when the gene data becomes larger.
Keywords :
approximation theory; biocomputing; cost reduction; optimisation; DNA sequences; approximate tandem repeats; gene analysis; genomic sequences; optimized algorithm; runtime cost reduction; Algorithm design and analysis; Bioinformatics; Biology; Computer science; Costs; DNA; Educational technology; Genetics; Runtime; Sequences; DNA sequence mining; approximate tandem repeat; motif-similarity;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Education Technology and Computer Science (ETCS), 2010 Second International Workshop on
Conference_Location :
Wuhan
Print_ISBN :
978-1-4244-6388-6
Electronic_ISBN :
978-1-4244-6389-3
Type :
conf
DOI :
10.1109/ETCS.2010.602
Filename :
5459976
Link To Document :
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