• DocumentCode
    2302275
  • Title

    An Optimized Algorithm for Finding Approximate Tandem Repeats in DNA Sequences

  • Author

    Li, Sheng ; Jiang, Qingshan ; Wei, Dan

  • Author_Institution
    Software Sch., Xiamen Univ., Xiamen, China
  • Volume
    3
  • fYear
    2010
  • fDate
    6-7 March 2010
  • Firstpage
    68
  • Lastpage
    71
  • Abstract
    In gene analysis, finding approximate tandem repeats in DNA sequence is an important issue. MSATR is one of the latest methods for finding those repetitions, which suffers deficiencies of runtime cost and poor result quality. This paper proposes an optimized algorithm mMSATR for detecting approximate tandem repeats in genomic sequences more efficiently. By introducing the definition of CASM to reduce the searching scope and optimizing the original mechanism adopted by MSATR, mMSATR makes the detecting process more efficient and improves the result quality. The theoretical analysis and experiment results indicates that mMSATR is able to get more results within less runtime. Algorithm mMSATR is superior to other methods in finding results, and it greatly reduces the runtime cost, which is of benefit when the gene data becomes larger.
  • Keywords
    approximation theory; biocomputing; cost reduction; optimisation; DNA sequences; approximate tandem repeats; gene analysis; genomic sequences; optimized algorithm; runtime cost reduction; Algorithm design and analysis; Bioinformatics; Biology; Computer science; Costs; DNA; Educational technology; Genetics; Runtime; Sequences; DNA sequence mining; approximate tandem repeat; motif-similarity;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Education Technology and Computer Science (ETCS), 2010 Second International Workshop on
  • Conference_Location
    Wuhan
  • Print_ISBN
    978-1-4244-6388-6
  • Electronic_ISBN
    978-1-4244-6389-3
  • Type

    conf

  • DOI
    10.1109/ETCS.2010.602
  • Filename
    5459976