DocumentCode
2302275
Title
An Optimized Algorithm for Finding Approximate Tandem Repeats in DNA Sequences
Author
Li, Sheng ; Jiang, Qingshan ; Wei, Dan
Author_Institution
Software Sch., Xiamen Univ., Xiamen, China
Volume
3
fYear
2010
fDate
6-7 March 2010
Firstpage
68
Lastpage
71
Abstract
In gene analysis, finding approximate tandem repeats in DNA sequence is an important issue. MSATR is one of the latest methods for finding those repetitions, which suffers deficiencies of runtime cost and poor result quality. This paper proposes an optimized algorithm mMSATR for detecting approximate tandem repeats in genomic sequences more efficiently. By introducing the definition of CASM to reduce the searching scope and optimizing the original mechanism adopted by MSATR, mMSATR makes the detecting process more efficient and improves the result quality. The theoretical analysis and experiment results indicates that mMSATR is able to get more results within less runtime. Algorithm mMSATR is superior to other methods in finding results, and it greatly reduces the runtime cost, which is of benefit when the gene data becomes larger.
Keywords
approximation theory; biocomputing; cost reduction; optimisation; DNA sequences; approximate tandem repeats; gene analysis; genomic sequences; optimized algorithm; runtime cost reduction; Algorithm design and analysis; Bioinformatics; Biology; Computer science; Costs; DNA; Educational technology; Genetics; Runtime; Sequences; DNA sequence mining; approximate tandem repeat; motif-similarity;
fLanguage
English
Publisher
ieee
Conference_Titel
Education Technology and Computer Science (ETCS), 2010 Second International Workshop on
Conference_Location
Wuhan
Print_ISBN
978-1-4244-6388-6
Electronic_ISBN
978-1-4244-6389-3
Type
conf
DOI
10.1109/ETCS.2010.602
Filename
5459976
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