• DocumentCode
    2305713
  • Title

    Automated vision-based force measurement of moving C. elegans

  • Author

    Ghanbari, Ali ; Nock, Volker ; Blaikie, Richard ; Chen, XiaoQi ; Chase, J. Geoffrey ; Wang, Wenhui

  • Author_Institution
    Department of Mechanical Engineering, University of Canterbury, Private Bag 4800, Christchurch 8140, New Zealand
  • fYear
    2010
  • fDate
    21-24 Aug. 2010
  • Firstpage
    198
  • Lastpage
    203
  • Abstract
    this paper reports an automated tracking and force measurement system for C. elegans in motion, based on microscopy computer vision. A polydimethylsiloxane (PDMS) device was microfabricated to allow C. elegans to move in a matrix of micropillars in a channel. An image processing algorithm has been developed to track the worm and deflecting micropillars automatically in purpose of quantifying multipoint locomotive forces of a moving C. elegans. The developed system is able to visually resolve force with a 0.33 µN resolution. A maximum force level of 55.41 µN for a young adult wild type C. elegans was observed.
  • Keywords
    Force; Force measurement; Grippers; Image resolution; Muscles; Tracking; Transforms;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Automation Science and Engineering (CASE), 2010 IEEE Conference on
  • Conference_Location
    Toronto, ON
  • Print_ISBN
    978-1-4244-5447-1
  • Type

    conf

  • DOI
    10.1109/COASE.2010.5584225
  • Filename
    5584225