Title :
Double Tilted Fiber Bragg Grating for label-free DNA detection
Author :
Candiani, Alessandro ; Sozzi, Michele ; Coscelli, Enrico ; Poli, Federica ; Ucinotta, Annamaria ; Selleri, Stefano ; Veneziano, Rosanna ; Corradini, Roberto ; Marchelli, Rosangela ; Childs, Paul ; Pissadakis, Stavros
Author_Institution :
Inf. Eng. Dept., Univ. of Parma, Parma, Italy
Abstract :
We present a new approach for developing a label-free biosensor for detection of DNA. The biosensor based on a biofunctionalized Double Tilt Fiber Bragg Grating transduces the presence of DNA into a change of visibility of fringes of its interference spectrum. Real-time spectral measurement results are reported, showing that a 10nM DNA solution induces a 10% modulation of the corresponding fringes visibility.
Keywords :
Bragg gratings; DNA; bio-optics; biomedical transducers; biosensors; fibre optic sensors; light interference; molecular biophysics; biofunctionalized transducers; biosensor; double tilted fiber Bragg grating; fringe visibility; interference spectrum; label-free DNA detection; real-time spectral measurement; Biosensors; Bragg gratings; DNA; Optical fiber sensors; Optical fibers; Refractive index;
Conference_Titel :
BioPhotonics, 2011 International Workshop on
Conference_Location :
Parma
Print_ISBN :
978-1-4244-9836-9
Electronic_ISBN :
978-1-4244-9835-2
DOI :
10.1109/IWBP.2011.5954849
