Modelling biochemical interactions in a microfluidic assisted porous silicon microarray for optical sensing

Author

Orabona, Emanuele ; Rea, Ilaria ; Rendina, Ivo ; De Stefano, Luca

Author_Institution

Inst. for Microelectron. & Microsyst., Nat. Res. Council, Naples, Italy

fYear

2011

fDate

8-10 June 2011

Firstpage

1

Lastpage

3

Abstract

In this paper we present a numerical model for the design of microfluidic assisted porous silicon microarray for the optical monitoring of biomolecular interactions. The kinetic binding is studied as a function of several physical, chemical and geometrical parameters. Optimization conditions in order to maximize the sensor response and increase the accuracy are given.

Keywords

bioMEMS; biochemistry; elemental semiconductors; microfluidics; numerical analysis; optical sensors; optimisation; physiological models; porous semiconductors; silicon; Si; biomolecular interactions; chemical parameters; geometrical parameters; kinetic binding; microfluidic assisted porous silicon microarray; modelling biochemical interactions; optical monitoring; optical sensing; optimization conditions; sensor response; Biomedical optical imaging; Chemicals; Finite element methods; Mathematical model; Microfluidics; Optical device fabrication; Silicon;

fLanguage

English

Publisher

ieee

Conference_Titel

BioPhotonics, 2011 International Workshop on

Conference_Location

Parma

Print_ISBN

978-1-4244-9836-9

Electronic_ISBN

978-1-4244-9835-2

Type

conf

DOI

10.1109/IWBP.2011.5954860

Filename

5954860