Title :
Comparing biosensors
Author :
Lading, Lars ; Nielsen, Lars Bjarne ; Sevel, Torben
Author_Institution :
Sensor Technol. Center, Brondby, Denmark
Abstract :
A methodology for comparing biosensors is discussed. Novel schemes are identified and compared with well-known concepts. Major sources of uncertainty are identified The biochemical process is characterized by quantum efficiency. The methodology is applied to evanescent wave based sensing devices, to surface plasmon devices, and to mechanically oscillating systems. A figure of merit is given in terms of the lowest change in a biologically active substance that can be detected.
Keywords :
Mach-Zehnder interferometers; biosensors; crystal resonators; integrated optics; microbalances; optical sensors; surface plasmons; Mach-Zehnder interferometer; biochemical process characterization; biosensor comparison methodology; electromechanical mechanical oscillator; evanescent wave based sensing devices; figure of merit; integrated optics; mechanically oscillating systems; optical methods; quantum efficiency; quartz microbalance; surface plasmon devices; Biosensors; Optical surface waves; Plasmons; Refractive index; Resonance; Sensor phenomena and characterization; Surface fitting; Surface waves; Thermal force; Volume measurement;
Conference_Titel :
Sensors, 2002. Proceedings of IEEE
Print_ISBN :
0-7803-7454-1
DOI :
10.1109/ICSENS.2002.1037088
