Title :
Highly ordered titania (TiO2) nanotube arrays fabricated by electrochemical self-ordering process toward development of implantable drug delivery devices with triggered drug release
Author :
Gulati, Karan ; Simovic, Spomenka ; Losic, Dusan
Author_Institution :
Ian Wark Res. Inst., Univ. of South Australia Mawson Lakes, Mawson Lakes, SA, Australia
Abstract :
The attractiveness of sell-ordered electrochemical synthesis of nanopore and nanotube arrays is based on its´ simplicity, low cost and nanoscale precision to create highly-organized and uniform structures with controllable dimensions and unique properties. In this work the fabrication of titania nanotubes (TNT) array and their application as implantable drug delivery platform is explored. Prepared TNT were loaded with anti-inflammatory drug (indomethacin). Sustained drug release including triggered release by external magnetic field from TNT implant was monitored by UV-VIS and reflective interference spectroscopy.
Keywords :
arrays; biomedical materials; drugs; electrochemistry; nanofabrication; nanomedicine; nanotubes; prosthetics; titanium compounds; TiO2; UV-VIS spectroscopy; electrochemical self-ordering; highly ordered titania nanotube arrays; implantable drug delivery; nanopore arrays; nanotube arrays; reflective interference spectroscopy; sell-ordered electrochemical synthesis; triggered drug release; Biomedical imaging; Biomedical monitoring; Magnetic properties; Magnetic resonance imaging; Monitoring;
Conference_Titel :
Optoelectronic and Microelectronic Materials and Devices (COMMAD), 2010 Conference on
Conference_Location :
Canberra, ACT
Print_ISBN :
978-1-4244-7334-2
Electronic_ISBN :
1097-2137
DOI :
10.1109/COMMAD.2010.5699716