• DocumentCode
    2315100
  • Title

    Utilization of NIR spectroscopy in candesartan cilexetil stability study

  • Author

    Dohnal, Jiri ; Jampilek, Josef ; Oktabec, Zbynek ; Zerzanova, Anna ; Kral, Vladimir

  • Author_Institution
    Zentiva a.s.z., Prague, Czech Republic
  • fYear
    2009
  • fDate
    21-25 Sept. 2009
  • Firstpage
    1
  • Lastpage
    1
  • Abstract
    For formulation of candesartan cilexetil and for its stabilization in dosage form was used the coating/complexation by macrogol. NIR spectrometry was utilized for analysis of development samples to optimize ratios candesartan cilexetil and macrogol. The stable dosage form was developed by means of the NIR spectrometry.
  • Keywords
    chemical analysis; infrared spectroscopy; NIR spectrometry; NIR spectroscopy; candesartan cilexetil stability study; macrogol; near-infrared spectroscopy; Chemical analysis; Chemical engineering; Chemical technology; Chemistry; Coatings; Degradation; Drugs; Pharmaceuticals; Spectroscopy; Stability;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Infrared, Millimeter, and Terahertz Waves, 2009. IRMMW-THz 2009. 34th International Conference on
  • Conference_Location
    Busan
  • Print_ISBN
    978-1-4244-5416-7
  • Electronic_ISBN
    978-1-4244-5417-4
  • Type

    conf

  • DOI
    10.1109/ICIMW.2009.5324624
  • Filename
    5324624