Title :
Colored petri nets to model gene mutation classification
Author :
Yang, Jinliang ; Gao, Rui ; Meng, Max Q -H ; Tarn, Tzyh-Jong
Author_Institution :
Sch. of Control Sci. & Eng., Shandong Univ., Jinan, China
Abstract :
The genetic code is the triplet code based on the three-letter codons. Choosing a feasible model for processing these codons is a useful method to study genetic processes in molecular biology. As an effective model of discrete event dynamic systems (DEDS), Colored Petri Net (CPN) has been used for modeling several biological systems. According to the genetic code table, CPN is employed to model the process of genetic information transmission. In this paper, we propose a CPN model to classify the type of gene mutations via contrasting the bases of DNA strands and the codons of amino acids along the polypeptide chain. This model is helpful in determining whether a certain gene mutation will cause the changes of the structures and functions of protein molecules. The effectiveness and accuracy of the presented model are illustrated by the examples in this paper.
Keywords :
DNA; Petri nets; discrete event systems; genetics; molecular biophysics; pattern classification; proteins; CPN model; DEDS; DNA strand; amino acid; biological system; colored Petri net; discrete event dynamic system; gene mutation classification; genetic code table; genetic information transmission; genetic process; molecular biology; polypeptide chain; protein molecule; three-letter codon; triplet code; Amino acids; Biological system modeling; Color; DNA; Modeling; Proteins; Amino acid codon; Gene mutation; Genetic information transmission; Molecular biology; Type classification;
Conference_Titel :
Intelligent Control and Automation (WCICA), 2012 10th World Congress on
Conference_Location :
Beijing
Print_ISBN :
978-1-4673-1397-1
DOI :
10.1109/WCICA.2012.6359440