Statistical analysis in complex-valued wavelet analysis of voltage-sensitive dye mapping

The aim of this study is to learn more about influence of the voltage sensitive dye to the tissue during optical mapping experiments on isolated animal hearts. There were recordings from all phases of the experiment examined to exclude possible negative influence of the dye to the tissue. Consecutive individual heart cycles extracted from ECG signals were transformed to time-frequency domain and divided into parts corresponding to P-Q segments, QRS complexes, and ST-T segments in each experimental period. Changes in ECG cycles caused by voltage sensitive dye application were studied during experimental phases. The statistical analysis were performed in time-frequency domain and compared.