A tissue-level electromechanical model of the left ventricle: Application to the analysis of intraventricular pressure

Author

Rolle, V. Le ; Hernández, AI ; Richard, P.-Y. ; Pibarot, P. ; Durand, L.-G. ; Carrault, G.

Author_Institution

INSERM, Rennes

fYear

2007

fDate

Sept. 30 2007-Oct. 3 2007

Firstpage

669

Lastpage

672

Abstract

This paper presents a model-based method for the analysis of experimental intraventricular pressure. The proposed approach is composed of a ventricular model and an identification algorithm. A multi-formalism, tissue-level electromechanical model of the left ventricle is proposed. Parameter identification is based on evolutionary algorithms and is applied to reproduce experimental pressures obtained from three pigs in steady-state conditions, during afterload variations and during ischemia. Identification results show the capability of the model to reproduce observed intraventricular pressure morphologies and to assist in the interpretation of these signals.

Keywords

biological tissues; cardiovascular system; haemodynamics; evolutionary algorithm; intraventricular pressure; ischemia; left ventricle; parameter identification; pigs; tissue level electromechanical model; Artificial intelligence; Calcium; Cardiology; Evolutionary computation; Ischemic pain; Morphology; Myocardium; Parameter estimation; Steady-state; Tensile stress;

fLanguage

English

Publisher

ieee

Conference_Titel

Computers in Cardiology, 2007

Conference_Location

Durham, NC

ISSN

0276-6547

Print_ISBN

978-1-4244-2533-4

Electronic_ISBN

0276-6547

Type

conf

DOI

10.1109/CIC.2007.4745574

Filename

4745574