Title :
THz-TDS studies on proteins and molecular complexes in solutions
Author :
Tominaga, Keisuke ; Kawaguchi, Shintaro ; Shibata, Mikihiro ; Kandori, Hideki ; Dutta, Partha
Abstract :
We have investigated low-frequency spectra of various systems in condensed phases by terahertz time-domain spectroscopy (THz-TDS). Low-frequency dynamics of bacteriorhodopsin is studied by changing the amount of hydration and temperature. A hydrated sample shows a sudden change in the THz spectrum at -40degC, although a dried sample does not show any change during the temperature change. For the solute/solvent systems we measured solutions of polar solutes in non-polar solvents to extract microscopic information on the interaction between the solute and solvent.
Keywords :
proteins; solvation; terahertz spectroscopy; terahertz wave spectra; bacteriorhodopsin hydration; bacteriorhodopsin low frequency dynamics; bacteriorhodopsin temperature; low frequency spectra; nonpolar solvents; polar solutes; solute-solvent systems; solution phase molecular complex spectroscopy; solution phase protein spectroscopy; temperature -40 degC; terahertz time domain spectroscopy; Absorption; Crystals; Frequency; Proteins; Refractive index; Resonance; Solvents; Spectroscopy; Temperature; Time domain analysis;
Conference_Titel :
Infrared, Millimeter, and Terahertz Waves, 2009. IRMMW-THz 2009. 34th International Conference on
Conference_Location :
Busan
Print_ISBN :
978-1-4244-5416-7
Electronic_ISBN :
978-1-4244-5417-4
DOI :
10.1109/ICIMW.2009.5325522
