Kinetic release of levodopa from Zn/Al-layered double hydroxide host

Author

Hussein, Mohd Zobir ; Ghani, Sarinawani Abdul ; Abdullah, A.H.

Author_Institution

Adv. Mater. & Nanotechnol. Lab., Univ. Putra Malaysia, Serdang, Malaysia

fYear

2010

fDate

1-3 Dec. 2010

Firstpage

1

Lastpage

2

Abstract

Kinetic release of Levodopa from Zn/Al-layered double hydroxide host is reported. The levodopa (LD) is an organic guest, is intercalated into the Zn-Al-layered double hydroxide lamella and was synthesized using direct co-precipitation method at pH 7.5 and Zn to Al molar ratio of 4, aged for 18 h at 70 ^οC. Release study of the levodopa from nanohybrid into various concentrations of sodium carbonate and sodium chloride solutions was studied using uv-visible spectroscopic method.

Keywords

aluminium compounds; biomedical materials; intercalation compounds; nanobiotechnology; nanocomposites; nanofabrication; organic compounds; organic-inorganic hybrid materials; pH; precipitation; spectrochemical analysis; ultraviolet spectra; visible spectra; zinc compounds; 3-(3,4-dihydroxyphenil)-L-alanine; UV-visible spectroscopy; Zn(OH)₂-Al(OH)₃; direct coprecipitation method; drug delivery; intercalation compounds; layered double hydroxide host; levodopa; organic-inorganoc hybrid type nanolayered composites; pH; sodium carbonate solution; sodium chloride solution;

fLanguage

English

Publisher

ieee

Conference_Titel

Enabling Science and Nanotechnology (ESciNano), 2010 International Conference on

Conference_Location

Kuala Lumpur

Print_ISBN

978-1-4244-8853-7

Type

conf

DOI

10.1109/ESCINANO.2010.5700963

Filename

5700963