Bacteria growth monitoring through an on-chip capacitive sensor

Author

Ghafar-Zadeh, Ebrahim ; Sawan, Mohamad ; Shabani, Arghavan ; Zourob, Mohammed ; Chodavarapu, Vamsy

Author_Institution

Polystim Neurotechnologies Lab., Ecole Polytechnque de Montreal, Montreal, QC

fYear

2008

fDate

18-20 June 2008

Firstpage

1

Lastpage

4

Abstract

In this paper, a charge based capacitive biosensor is presented for bacteria growth monitoring (BGM). This sensor chip is implemented through CMOS process in order to show the applicability of the proposed on-chip capacitive technique for BGM purposes. The passivated interdigitated electrodes atop CMOS chip are exposed to Escherichia coli (Ecoli) bacteria in the channel. The presence of bacteria in proximity of electrode causes a minute change in double layer capacitance. The variation of this capacitance (DeltaC<60 pF) versus time is demonstrated and compared with conventional impedance-based technique.

Keywords

biological techniques; biosensors; capacitance; capacitive sensors; interdigital transducers; microorganisms; CMOS chip; Escherichia coli; bacteria growth monitoring; biosensor; double layer capacitance; interdigitated electrodes; on-chip capacitive sensor; passivation; sensor chip; Biosensors; CMOS process; Capacitance measurement; Capacitive sensors; Electrodes; Impedance measurement; Microorganisms; Monitoring; Pollution measurement; Semiconductor device measurement;

fLanguage

English

Publisher

ieee

Conference_Titel

Mixed-Signals, Sensors, and Systems Test Workshop, 2008. IMS3TW 2008. IEEE 14th International

Conference_Location

Vancouver, BC

Print_ISBN

978-1-4244-2395-8

Electronic_ISBN

978-1-4244-2396-5

Type

conf

DOI

10.1109/IMS3TW.2008.4581606

Filename

4581606