Title :
An HV-CMOS Integrated Circuit for Neural Stimulation in Prosthetic Applications
Author :
Bisoni, Lorenzo ; Carboni, Caterina ; Raffo, Luigi ; Carta, Nicola ; Barbaro, Massimo
Author_Institution :
Dept. of Electr. & Electron. Eng., Univ. di Cagliari, Cagliari, Italy
Abstract :
An integrated neural stimulator for prosthetic applications, realized with a high-voltage CMOS 0.35-μm process, is presented. The device is able to provide biphasic current pulses to stimulate eight electrodes independently. A voltage booster generates a 17-V voltage supply in order to guarantee the programmed stimulation current even in case of high impedances at the electrode-tissue interface. Pulse parameters such as amplitude, frequency, and width can be programmed digitally. The device has been successfully tested by means of both electrical and in vivo tests, and the results show its capability to provide currents on the order of hundreds of microamperes with impedances on the order of tens of kiloohms.
Keywords :
CMOS integrated circuits; bioelectric potentials; biological tissues; biomedical electrodes; biomedical electronics; neurophysiology; prosthetics; HV-CMOS integrated circuit; biphasic current pulses; electrical tests; electrode-tissue interface; high-voltage CMOS process; in vivo tests; integrated neural stimulator; neural stimulation; programmed stimulation current; prosthetic applications; pulse amplitude; pulse frequency; pulse parameters; pulse width; size 0.35 mum; voltage 17 V; voltage booster; Capacitors; Clocks; Electrodes; Integrated circuits; Switches; Transistors; Voltage control; Biomedical interfaces; Neural stimulation; PNS stimulation; high voltage stimulator; high-voltage (HV) stimulator; neural stimulation; peripheral neural stimulation (PNS); voltage booster;
Journal_Title :
Circuits and Systems II: Express Briefs, IEEE Transactions on
DOI :
10.1109/TCSII.2014.2387679
