Title :
CMOS readout electronics for an emission-transmission medical imaging system
Author :
Heanue, J.A. ; Boser, B.E. ; Hasegawa, B.H.
Author_Institution :
Dept. of Electr. Eng. & Comput. Sci., California Univ., Berkeley, CA, USA
fDate :
30 Oct-5 Nov 1994
Abstract :
We have developed a CMOS chip for readout of a germanium detector in an emission-transmission medical imaging system. The chip can be operated in three different modes. First, there is a slow pulse counting mode for acquisition of radionuclide data at 104 cps/channel and 1-2 keV energy resolution. Next, there is a fast pulse counting mode for collection of dual-energy X-ray data or for simultaneous accumulation of radionuclide emission and X-ray transmission counts at 106 cps and 5-7 keV energy resolution. Finally, there is a current mode readout for fast acquisition of X-ray transmission data. The new readout electronics offer the potential for improved quantitation of SPECT data. Monte Carlo simulations indicate that 2 keV energy resolution is sufficient to reduce the uncertainty due to scatter to below the level of uncertainty due to photon statistics. In addition, the X-ray data can be used to generate an object-specific attenuation map at the radionuclide energy. Thus, the new electronics offer the possibility of virtually scatter-free, attenuation-corrected quantitative SPECT images
Keywords :
CMOS integrated circuits; Monte Carlo methods; application specific integrated circuits; biomedical electronics; cardiology; computerised tomography; detector circuits; digital readout; nuclear electronics; single photon emission computed tomography; ASIC; CMOS readout electronics; Ge detector readout; Monte Carlo simulations; SPECT data; X-ray CT; X-ray transmission counts; X-ray transmission data acquisition; attenuation-corrected quantitative SPECT images; current mode readout; dual-energy X-ray data; emission transmission CT system; emission-transmission medical imaging system; energy resolution; fast pulse counting mode; myocardial phantom; object-specific attenuation map; photon statistics uncertainty level; radionuclide data acquisition; slow pulse counting mode; Biomedical imaging; Detectors; Electromagnetic scattering; Energy resolution; Germanium; Particle scattering; Readout electronics; Single photon emission computed tomography; Uncertainty; X-ray scattering;
Conference_Titel :
Nuclear Science Symposium and Medical Imaging Conference, 1994., 1994 IEEE Conference Record
Conference_Location :
Norfolk, VA
Print_ISBN :
0-7803-2544-3
DOI :
10.1109/NSSMIC.1994.474723
