1F-2 Optical Trapping of Ultrasound Contrast Agent Microbubbles: Study of the Bubble-Wall and Bubble-Bubble Interaction in Ultrasound

Author

Garbin, V. ; Ferrari, E. ; Cojoc, D. ; Fabrizio, E. Di ; Overvelde, M.L.J. ; van der Meer, S.M. ; Versluis, M. ; de Jong, N. ; Lohse, D.

Author_Institution

TASC, INFM, Trieste

fYear

2006

fDate

2-6 Oct. 2006

Firstpage

513

Lastpage

516

Abstract

Here we present optical tweezers as a micromanipulation tool for the study of ultrasound contrast agent (UCA) microbubbles. Optical trapping and the resulting manipulation of individual and multiple microbubbles enables the study of their dynamics with controlled boundary conditions. The bubble response to ultrasound is recorded optically using the ultra high-speed Brandaris 128 camera. In our experiments, the amplitude of bubble oscillations was found to be strongly influenced by the vicinity of the sample chamber wall. Experiments with two trapped bubbles also showed a considerable influence of the neighboring bubble on the amplitude of oscillations of the other one

Keywords

bubbles; micromanipulators; radiation pressure; ultrasonics; Brandaris 128 camera; bubble oscillations; bubble-bubble interaction; bubble-wall interaction; micromanipulation tool; optical trapping; optical tweezers; ultrasound contrast agent microbubbles; Charge carrier processes; High speed optical techniques; Laser beams; Optical interferometry; Optical modulation; Optical refraction; Optical scattering; Optical variables control; Optical vortices; Ultrasonic imaging;

fLanguage

English

Publisher

ieee

Conference_Titel

Ultrasonics Symposium, 2006. IEEE

Conference_Location

Vancouver, BC

ISSN

1051-0117

Print_ISBN

1-4244-0201-8

Electronic_ISBN

1051-0117

Type

conf

DOI

10.1109/ULTSYM.2006.136

Filename

4151992