• DocumentCode
    2355878
  • Title

    The effect of surface properties of gold nanoparticles on cellular uptake

  • Author

    Yang, Jing ; Zeng, Jie ; Kong, Tao ; Wang, Xiaoping ; Roa, Wilson ; El-Bialy, T. ; Xing, James ; Chen, Jie

  • Author_Institution
    Alberta Univ., Edmonton
  • fYear
    2007
  • fDate
    8-9 Nov. 2007
  • Firstpage
    92
  • Lastpage
    95
  • Abstract
    In this study, we developed GNPs with various types of chemical surface features and evaluated how these features led nanoparticles to selectively bind to different target cell sites. Results showed that selective binding was successful in producing high concentrations in target locations. We also explored the potential application of these GNPs to enhance the cancer cell cytotoxicity induced by radiotherapy.
  • Keywords
    biomedical materials; cancer; cellular biophysics; gold; nanobiotechnology; nanoparticles; radiation therapy; Au; cancer cell cytotoxicity; cellular uptake; chemical surface features; nanoparticles; radiotherapy; Conferences; Gold; Nanoparticles;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Life Science Systems and Applications Workshop, 2007. LISA 2007. IEEE/NIH
  • Conference_Location
    Bethesda, MD
  • Print_ISBN
    978-1-4244-1813-8
  • Electronic_ISBN
    978-1-4244-1813-8
  • Type

    conf

  • DOI
    10.1109/LSSA.2007.4400892
  • Filename
    4400892
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=2355878