Testing the quality of 12 lead holter analysis algorithms

Computer assisted analysis of ECGs has recently experienced a remarkable revival due to its increased importance as biomarker in clinical trials. Especially 12-lead 24 h Holter-recording is nowadays routinely applied. But how accurate is the automatic computer analysis of 12 lead Holter recordings? While there are several data bases to evaluate the performance of 2-lead Holter algorithms, e.g., MIT-BIH, AHA etc., to our knowledge, there is no annotated data base for real 12-lead Holter algorithms. We have therefore created a new 12 lead ECG database containing 50 Holter ECGs from the University Hospital Munich, Campus Grosshadern. The following paper describes the data base and its application for evaluating different 12 lead Holter analysis algorithms in detail.