A laser scattering method for characterization of thromboemboli in whole blood

Author

Kim, Jungkuk ; Lin, James C. ; Reynolds, Larry O.

Author_Institution

Bioeng. Program, Illinois Univ., Chicago, IL, USA

fYear

1994

fDate

1994

Firstpage

1003

Abstract

An optical scattering method, which measures the size, number, and type of microemboli located in flowing whole blood, is described. A perturbation solution to the one speed radiative transport equation is used to model the scattering geometry. The approximate two-parameter phase function is used to investigate scattering characteristics of microemboli. The nature of microemboli is determined by comparing the scattered intensity ratio in two forward directions, while the size and number are determined by considering intensities scattered perpendicularly to the incident direction. This method has been tested with several sizes of polystyrene spheres, air bubbles, and blood dots. The results showed excellent agreement with calculations

Keywords

light scattering; air bubbles; approximate two-parameter phase function; blood dots; laser scattering method; one speed radiative transport equation; optical scattering method; perturbation solution; polystyrene spheres; scattered intensity ratio; thromboemboli characterization; whole blood; Biological materials; Biomedical engineering; Detectors; Equations; Geometrical optics; Laser theory; Light scattering; Monitoring; Particle scattering; Red blood cells;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1994. Engineering Advances: New Opportunities for Biomedical Engineers. Proceedings of the 16th Annual International Conference of the IEEE

Conference_Location

Baltimore, MD

Print_ISBN

0-7803-2050-6

Type

conf

DOI

10.1109/IEMBS.1994.415255

Filename

415255