Title :
Electrodynamic mechanism of voltage dependent gating
Author :
Chernyak, Yuri B.
Author_Institution :
Div. of Health Sci. & Technol., MIT, Cambridge, MA, USA
Abstract :
A new concept of channel gating is proposed. The concept is based on the idea that the polarization of the channel, due to the presence of gating charges, modifies the effective potential through which the ions migrate. The channel gate is therefore an up or down shift in the potential function seen by the ion in the channel
Keywords :
bioelectric potentials; biomembrane transport; calcium; cellular biophysics; electrodynamics; potassium; sodium; Ca; Ca currents; K; K currents; Na; Na currents; channel gating; channel polarization; effective potential; electrodynamic mechanism; gating charges; ion migration; membrane potential; potential function; voltage dependent gating; Biomembranes; Charge measurement; Current measurement; Electrodynamics; Equations; Polarization; Steady-state; Strips; Vectors; Voltage;
Conference_Titel :
Engineering in Medicine and Biology Society, 1994. Engineering Advances: New Opportunities for Biomedical Engineers. Proceedings of the 16th Annual International Conference of the IEEE
Conference_Location :
Baltimore, MD
Print_ISBN :
0-7803-2050-6
DOI :
10.1109/IEMBS.1994.415262
