Title :
Semi-automatic enhancement of atrial models to include atrial architecture and patient specific data: For biophysical simulations
Author :
Hermosillo, BD Flores
Author_Institution :
Dept. of Comput. Sci., Hull Univ., Kingston upon Hull
Abstract :
Despite its large influence on biophysical simulations, the underlying anatomical representation is often oversimplified. The need for mode detailed anatomical models has been identified by numerous authors. An atrial model including macro and microscopic muscle architecture would help improve the correlation between real and virtual ECGs. In addition it provides a mean to de-couple the simulation domains (anatomy and physiology). A tool developed to create such models is presented. It readily allows fine-tuning factors such as: connectivity, discontinuity, fiber orientation, muscle architecture, and heterogeneities. The algorithms that speed up the conversion of a 3D heart mesh in raw format, into a detailed model of the atria are explained. As a result, patient-specific models are brought one step closer.
Keywords :
biology computing; electrocardiography; medical signal processing; mesh generation; muscle; 3D heart mesh; anatomical models; atrial architecture; atrial models; biophysical simulations; connectivity; discontinuity; fiber orientation; fine-tuning factors; heterogeneity; macroscopic muscle; microscopic muscle architecture; patient specific data; semiautomatic enhancement; virtual ECGs; Aggregates; Anatomy; Biological system modeling; Electrocardiography; Geometry; Heart; Magnetic resonance imaging; Mathematical model; Microscopy; Muscles;
Conference_Titel :
Computers in Cardiology, 2008
Conference_Location :
Bologna
Print_ISBN :
978-1-4244-3706-1
DOI :
10.1109/CIC.2008.4749121