Broad-band neck suction in the assessment of the dynamics of the baroreflex-heart rate transfer in humans

Author

Pinna, G.D. ; Matestri, R. ; Mortara, A. ; Prpa, A. ; La Rovere, MT

Author_Institution

Dept. of Biomed. Eng., Rehabilitation Inst. of Montescano, Pavia, Italy

fYear

1998

fDate

13-16 Sep 1998

Firstpage

345

Lastpage

348

Abstract

In this study we applied broad-band neck suction (NES) stimulation to 11 healthy individuals and 10 chronic heart failure (CHF) patients, and performed a closed-loop estimation of the transfer magnitude characteristics (gain) of the carotid sinus baroreceptor-RR interval (RRI) reflex using a non-parametric frequency domain approach. The suction pressure, obtained through a servo-controlled pump, was 0÷-35 mmHg in the band 0÷0.35 Hz. We found a marked difference in the pattern of the gain between the two groups. Particularly, normal subjects showed a band-pass behavior centered at 0.1±0.01 Hz, whereas CHF patients showed a marked low-pass response in the VLF band with a progressive attenuation in the LF and HF bands. The coherence between NES and RRI was typically <0.5, which would imply a low precision of gain point estimates

Keywords

biocontrol; blood pressure measurement; cardiovascular system; closed loop systems; electrocardiography; feedforward; frequency-domain analysis; medical signal processing; neuromuscular stimulation; signal sampling; time series; transfer functions; VLF band; arterial blood pressure regulation; band-pass behavior; baroreflex-heart rate transfer dynamics; broadband neck suction stimulation; cardiovascular function; carotid sinus baroreceptor-RR interval reflex; cascade effect; chronic heart failure patients; closed-loop estimation; feedforward transfer; marked low-pass response; nonparametric frequency domain approach; progressive attenuation; transfer magnitude characteristics; Baroreflex reflex; Biomedical engineering; Blood pressure; Cardiology; Frequency estimation; Heart rate; Humans; Neck; Protocols; Rail to rail inputs;

fLanguage

English

Publisher

ieee

Conference_Titel

Computers in Cardiology 1998

Conference_Location

Cleveland, OH

ISSN

0276-6547

Print_ISBN

0-7803-5200-9

Type

conf

DOI

10.1109/CIC.1998.731805

Filename

731805