Title :
Optimal adjustment of the atrio-aortic left ventricular assist device (AA-LVAD)
Author :
Pilla, James J. ; Drzewiecki, G.M. ; Welkowitz, Walter
Author_Institution :
Dept. of Biomed. Eng., Rutgers Univ., Piscataway, NJ, USA
Abstract :
The authors document a protocol for optimal timing of the LVAD based on reduced heart oxygen consumption. Timing is studied using a closed-loop analog model of the heart, vascular system, and the LVAD. Results indicate that the pump should begin ejection immediately after the close of the aortic valve and that the pump filling pressure should pump set to a value which produces maximum filling of the pump and maximum ventricular unloading. The optimization of the pump ejection pressure is a trade-off between left-ventricular O2 and stroke volume and mean arterial pressure
Keywords :
artificial organs; cardiology; optimisation; aortic valve; atrio-aortic left ventricular assist device; closed-loop analog model; ejection; heart O2 consumption; mean arterial pressure; optimal adjustment; pump filling pressure; stroke volume; vascular system; Biomedical engineering; Blood pressure; Cardiology; Cardiovascular system; Circuits; Filling; Heart; Protocols; Timing; Valves;
Conference_Titel :
Bioengineering Conference, 1989., Proceedings of the 1989 Fifteenth Annual Northeast
Conference_Location :
Boston, MA
DOI :
10.1109/NEBC.1989.36702
