A fiber-optic technique to determine blood residence times and washout patterns in the Penn State artificial heart

Author

Franscischelli, D.E. ; Tarbell, J.M. ; Deutsch, S. ; Geselowitz, D.B.

Author_Institution

Pennsylvania State Univ., University Park, PA, USA

fYear

1989

fDate

27-28 Mar 1989

Firstpage

81

Lastpage

82

Abstract

Low shear regions tend to be sites of stasis or stagnation of blood cells. To quantify and evaluate the degree of stagnation, a flush-mountable fiber-optic probe was developed, and dye dilution techniques utilizing the fluorescent dye fluorescein were applied. This method allowed the washout patterns to be determined at several locations within the chamber, extending approximately 2 mm from the chamber wall. Both the 100-cm³ angle port and 70-cm³ parallel port chamber configurations were investigated under 30% and 50% systolic duration regimes

Keywords

artificial organs; biomedical measurement; blood; cardiology; fibre optics; Penn State artificial heart; angle port chamber; blood cells stagnation; blood residence time; dye dilution techniques; fibre optic technique; fluorescein; fluorescent dye; flush-mountable fiber-optic probe; parallel port chamber; washout pattern; Artificial heart; Biomedical engineering; Blood; Cells (biology); Chemical engineering; Coagulation; Laboratories; Probes; Prosthetics; Stress;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioengineering Conference, 1989., Proceedings of the 1989 Fifteenth Annual Northeast

Conference_Location

Boston, MA

Type

conf

DOI

10.1109/NEBC.1989.36708

Filename

36708