Title :
A CMOS integrated circuit for DNA hybridization detection with digital output and temperature control
Author :
Caboni, Alessandra ; Loi, Daniela ; Barbaro, Massimo
Author_Institution :
Univ. of Cagliari, Cagliari
Abstract :
A CMOS integrated circuit hosting an array of 80 sensors for DNA hybridization detection was designed. Each biosensor is made up of a FET device whose current is modulated by DNA electric charge. The chip incorporates integrated temperature detection for precise assay control and features programmable signal conditioning, amplification and A/D conversion. Successful pre- and post-layout simulations are provided.
Keywords :
CMOS integrated circuits; biosensors; temperature control; CMOS integrated circuit; DNA electric charge; DNA hybridization detection; FET device; biosensor; digital output; temperature control; Biosensors; CMOS integrated circuits; DNA; MOS devices; MOSFETs; Sensor arrays; Temperature control; Temperature sensors; Testing; Threshold voltage;
Conference_Titel :
Research in Microelectronics and Electronics Conference, 2007. PRIME 2007. Ph.D.
Conference_Location :
Bordeaux
Print_ISBN :
978-1-4244-1000-2
Electronic_ISBN :
978-1-4244-1001-9
DOI :
10.1109/RME.2007.4401830
