Autonomic nervous system effects on ventricular repolarization and RR interval variability during head-up tilt

Author

Shusterman, Vladimir ; Aysin, Benhur ; Shah, S. Ismail ; Flanigan, Susanne ; Anderson, Kelley P.

Author_Institution

Pittsburgh Univ., PA, USA

fYear

1998

fDate

13-16 Sep 1998

Firstpage

717

Lastpage

720

Abstract

Changes in ventricular repolarization (VR) were analyzed using 32-lead high spatial resolution ECGs (HSRE). FFT-derived low (0.04-0.15 Hz) and high (0.15-0.4 Hz) frequency powers (LF & HF, respectively) of RR interval variability (RRIV) and their ratio were used to assess changes in the autonomic activity elicited by 70° tilt in 9 patients with structural heart disease (SHD) and 19 control (CON) subjects. Heart rate (HR) increased with tilt in CON and SHD. HF and LF/HF increased with tilt in CON, but not in SHD. Peak and mean T-wave amplitudes declined with tilt in CON but not in SHD. In contrast to CON subjects, RRIV and VR failed to change in SHD patients despite increased HR. This suggests preserved tonic but reduced rhythmic autonomic nervous system activity (ANSA) related modulation of HR, and reduced ANSA effects on VR

Keywords

biomechanics; diseases; electrocardiography; medical signal processing; neurophysiology; 0.04 to 0.4 Hz; 32-lead high spatial resolution ECGs; RR interval variability; autonomic nervous system effects; electrodiagnostics; head-up tilt; rhythmic activity; structural heart disease; tonic activity; ventricular repolarization; Autonomic nervous system; Cardiac disease; Electrocardiography; Frequency; Hafnium; Heart rate; Helium; Spatial resolution; Testing; Virtual reality;

fLanguage

English

Publisher

ieee

Conference_Titel

Computers in Cardiology 1998

Conference_Location

Cleveland, OH

ISSN

0276-6547

Print_ISBN

0-7803-5200-9

Type

conf

DOI

10.1109/CIC.1998.731974

Filename

731974