DocumentCode :
2373385
Title :
In vitro cytotoxicity testing and the application of elastic interconnection technology for short-term implantable electronics
Author :
Brosteaux, Dominique ; Lippens, Evi ; Cornelissen, Ria ; Schacht, Etienne ; Carta, Riccardo ; Jourand, Philippe ; Puers, Robert ; Axisa, Fabrice ; Vervust, Thomas ; Bossuyt, Frederick ; Vanfleteren, Jan
Author_Institution :
IMEC, Ghent Univ., Ghent, Belgium
fYear :
2009
fDate :
3-6 Sept. 2009
Firstpage :
4880
Lastpage :
4883
Abstract :
An electronic device was fabricated consisting of 2 flexible electronic circuit islands, interconnected by a 7 cm long elastic interconnection, which could be elongated for at least 50%. This interconnection was based on gold conductor tracks following a 2-D spring pattern, embedded in a biocompatible silicone elastomer. The complete device was embedded in the same silicone elastomer. An in vitro cytotoxicity extraction test, executed on small test-samples in accordance with the ISO 10 993-1 guidelines, revealed that the applied silicone encapsulation to these samples functioned as a good seal for at least 8 days.
Keywords :
biomedical electronics; biomedical materials; conducting materials; gold; integrated circuit interconnections; polymers; prosthetics; 2-D spring pattern; ISO 10 993-1 guidelines; biocompatible silicone elastomer; elastic interconnection technology; flexible electronic circuit islands; gold conductor tracks; in vitro cytotoxicity extraction test; short-term implantable electronics; silicone encapsulation; Animals; Cell Survival; Cells, Cultured; Chickens; Electronics, Medical; Prostheses and Implants; Silicones;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE
Conference_Location :
Minneapolis, MN
ISSN :
1557-170X
Print_ISBN :
978-1-4244-3296-7
Electronic_ISBN :
1557-170X
Type :
conf
DOI :
10.1109/IEMBS.2009.5332457
Filename :
5332457
Link To Document :
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