Title :
A Novel gene detection method based on period-3 property
Author :
Huang, Lun ; Al Bataineh, Mohammad ; Atkin, G.E. ; Wang, Siyun ; Zhang, Wei
Author_Institution :
Dept. of Electr. & Comput. Eng., Illinois Inst. of Technol., Chicago, IL, USA
Abstract :
Processing of biomolecular sequences using communication theory techniques provides powerful approaches for solving highly relevant problems in bioinformatics by properly mapping character strings into numerical sequences. We provide an optimized procedure for predicting protein-coding regions in DNA sequences based on the period-3 property of coding region. We present a digital correlating and filtering approach in the process of predicting these regions, and find out their locations by using the magnitude of the output sequence. These approaches result in improved computational techniques for the solution of useful problems in genomic information science and technology.
Keywords :
DNA; bioinformatics; genomics; information theory; molecular biophysics; proteins; DNA sequences; bioinformatics; biomolecular sequences; communication theory; gene detection; genomics; period-3 property; protein-coding regions; Algorithms; Animals; Caenorhabditis elegans; Computational Biology; Computer Simulation; DNA; Exons; Fourier Analysis; Genomics; Humans; Models, Genetic; Models, Statistical; Models, Theoretical; RNA, Messenger; Sequence Analysis, DNA;
Conference_Titel :
Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE
Conference_Location :
Minneapolis, MN
Print_ISBN :
978-1-4244-3296-7
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2009.5332576